Preheat oven to 400˚F (200˚C). Line a large baking sheet with parchment or lightly grease.
Place the sugar in a large bowl and rub in the Meyer lemon zest until evenly blended.
Stir in the flour, baking powder, and salt.
Quickly cut in the butter using a dough blender, two forks, or your fingers until blended and no pieces are larger than a pea.
Mix in the cream, egg, Meyer lemon juice, and vanilla bean paste until just combined.
Knead lightly to bring the dough together, but don't overwork. If too dry, slowly add a little more cream. Be careful not to add too much liquid. The dough should hold its shape, but not become sticky.
Place the dough on a lightly floured surface and divide in half. Press each half into a disc about 3/4 inches (2 centimeters) thick. Cut each disc into 4 equal slices to make 8 scones in all.
Transfer the scones to the prepared baking sheet about 1 inch (2.5 centimeters) apart. Brush the tops lightly with additional cream, taking care to not let it drip down the sides.
Bake in the preheated oven until puffed and golden, about 10-12 minutes.
Allow to cool for 5 minutes before removing to wire rack and cool to room temperature before adding the glaze.